Chesnut, Gregory

Open Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
A Urine Exosome Gene Expression Panel Distinguishes between Indolent and Aggressive Prostate Cancers at Biopsy Coordinating 0 0
Biomarkers for Early Detection of Aggressive Prostate Cancer Involved 7 0
Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies independent predictors of recurrence Leading 0 0
Prostate Active Surveillance Study Involved 2 0
Prostate-MRI Involved 0 1
Proteomic Tissue-Based Classifier for Early Prediction of Prostate Cancer Progression Coordinating 0 0

Closed Protocols

Protocol Name Investigatory Role Biomarkers Data Collections
SELDI Phase I: Assay Validation-Prostate Involved 1 1
SELDI Validation Study Phase II Involved 1 1

Publications

Publication NamePubMed IDJournal
A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry. 32409115 Eur Urol
A novel genomic alteration of LSAMP associates with aggressive prostate cancer in African American men. 26844274 EBioMedicine
A Rich Array of Prostate Cancer Molecular Biomarkers: Opportunities and Challenges. 31013716 Int J Mol Sci
A Urine Exosome Gene Expression Panel Distinguishes between Indolent and Aggressive Prostate Cancers at Biopsy. 32945736 J Urol
African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer. 32930425 Int J Cancer
Analysis of <i>PMEPA1</i> Isoforms (<i>a</i> and <i>b</i>) as Selective Inhibitors of Androgen and TGF-β Signaling Reveals Distinct Biological and Prognostic Features in Prostate Cancer. 31842254 Cancers (Basel)
Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods. 25889691 J Transl Med
Association of germline genetic variants with <i>TMPRSS2-ERG</i> fusion status in prostate cancer. 32341752 Oncotarget
Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag. 28191285 Genes Cancer
Clinical potential of the ERG oncoprotein in prostate cancer. 22331093 Nat Rev Urol
Contemporary Management of Hemorrhage After Minimally Invasive Radical Prostatectomy. 31034916 Urology
Defining the index lesion for potential salvage partial or hemi-gland ablation after radiation therapy for localized prostate cancer. 33583697 Urol Oncol
Differences in frequency of ERG oncoprotein expression between index tumors of Caucasian and African American patients with prostate cancer. 22950997 Urology
Electronic Rapid Fitness Assessment Identifies Factors Associated with Adverse Early Postoperative Outcomes following Radical Cystectomy. Reply. 33591802 J Urol
ERG monoclonal antibody in the diagnosis and biological stratification of prostate cancer: delineation of minimal epitope, critical residues for binding, and molecular basis of specificity. 25170998 Monoclon Antib Immunodiagn Immunother
ERG oncoprotein expression in prostate carcinoma patients of different ethnicities. 25469265 Mol Clin Oncol
ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer. 25344575 Mol Cancer Res
ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer--a comparative study of two monoclonal antibodies. 22231490 Prostate Cancer Prostatic Dis
Ethnicity and ERG frequency in prostate cancer. 28872154 Nat Rev Urol
Evaluation of serum protein profiling by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry for the detection of prostate cancer: I. Assessment of platform reproducibility. 15613711 Clin Chem
Evolution in technique of robotic intracorporeal continent catheterizable pouch after cystectomy. 31893282 Urol Video J
Functional antagonism of TMPRSS2-ERG splice variants in prostate cancer. 25221645 Genes Cancer
Genetic and molecular differences in prostate carcinogenesis between African American and Caucasian American men. 23892597 Int J Mol Sci
Impact of caregiver overnight stay on postoperative outcomes. 31940152 Int J Health Care Qual Assur
Increased association of the ERG oncoprotein expression in advanced stages of prostate cancer in Filipinos. 24909781 Prostate
Increased frequency of germline BRCA2 mutations associates with prostate cancer metastasis in a racially diverse patient population. 30542053 Prostate Cancer Prostatic Dis
Isolated urethral metastasis from appendiceal mucinous adenocarcinoma. 32526660 Clin Imaging
Low Frequency of the ERG Oncogene Alterations in Prostate Cancer Patients from India. 23901346 J Cancer
Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies <i>ERG</i> as the strongest independent predictor of recurrence. 31741711 Oncotarget
Multi-omic serum biomarkers for prognosis of disease progression in prostate cancer. 31910880 J Transl Med
Patient-reported pain, discomfort, and anxiety during magnetic resonance imaging-targeted prostate biopsy. 31793867 Can Urol Assoc J
Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24. 34127801 Prostate Cancer Prostatic Dis
Philadelphia Prostate Cancer Genetic Consensus Conference 2019 and implications for military medicine. 34129457 Can J Urol
Predicting Prostate Cancer Progression as a Function of ETS-related Gene Status, Race, and Obesity in a Longitudinal Patient Cohort. 28753864 Eur Urol Focus
Predominance of ERG-negative high-grade prostate cancers in African American men. 25279185 Mol Clin Oncol
Prognostic features of Annexin A2 expression in prostate cancer. 32967771 Pathology
Proteomic Tissue-Based Classifier for Early Prediction of Prostate Cancer Progression. 32429558 Cancers (Basel)
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. 33473200 Nat Genet
Reply to Benjamin S. Simpson, Lina M. Carmona Echeverria, Joseph M. Norris, Hashim U. Ahmed, Caroline M. Moore, and Hayley C. Whitaker's Letter to the Editor re: Gregory T. Chesnut, Emily A. Vertosick, Nicole Benfante, et al. Role of Changes in Magne 32522388 Eur Urol
Reply to Jianhui Du, Yueguang Liu, and Weigang Yan's Letter to the Editor re: Gregory T. Chesnut, Emily A. Vertosick, Nicole Benfante, et al. Role of Changes in Magnetic Resonance Imaging or Clinical Stage in Evaluation of Disease Progression for Men 32386781 Eur Urol
Role of Changes in Magnetic Resonance Imaging or Clinical Stage in Evaluation of Disease Progression for Men with Prostate Cancer on Active Surveillance. 31874726 Eur Urol
SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer. 18024530 Clin Chem
Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection. 33997822 Eur Urol Open Sci
Standardizing Opioid Prescriptions to Patients After Ambulatory Oncologic Surgery Reduces Overprescription. 32499083 Jt Comm J Qual Patient Saf
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. 33398198 Nat Genet

Interests

No interests found at the present moment.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.