A micropapillary pattern is predictive of a poor prognosis in lung adenocarcinoma, and reduced surfactant apoprotein A expression in the micropapillary pattern is an excellent indicator of a poor prognosis. |
17431413 |
Mod Pathol |
Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125). |
16880776 |
Mod Pathol |
Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer. |
23446997 |
Clin Cancer Res |
Aberrant expression of transmembrane mucins, MUC1 and MUC4, in human prostate carcinomas. |
16302265 |
Prostate |
ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression. |
17721921 |
Int J Cancer |
Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates. |
17019794 |
Am J Clin Pathol |
Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins. |
17914743 |
J Cell Biochem |
CCL21 induces extensive intratumoral immune cell infiltration and specific anti-tumor cellular immunity. |
17273764 |
Int J Oncol |
Cell surface-associated mucins in signal transduction. |
16904320 |
Trends Cell Biol |
Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer. |
21860420 |
Oncogene |
Characterization of human mucin MUC17. Complete coding sequence and organization. |
16737958 |
J Biol Chem |
Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance. |
16207894 |
Glycobiology |
Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats. |
16405548 |
Am J Gastroenterol |
Class III beta-tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia. |
17714470 |
Histopathology |
Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer. |
19012856 |
Lancet Oncol |
Complete suppression of tumor formation by high levels of basement membrane collagen. |
18171981 |
Mol Cancer Res |
Concise review: recent advances on the significance of stem cells in tissue regeneration and cancer therapies. |
16794264 |
Stem Cells |
Culture and immortalization of pancreatic ductal epithelial cells. |
15542901 |
Methods Mol Med |
Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras. |
21825040 |
Clin Cancer Res |
Deregulation of MUC4 in gastric adenocarcinoma: potential pathobiological implication in poorly differentiated non-signet ring cell type gastric cancer. |
18781152 |
Br J Cancer |
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. |
22412968 |
PLoS One |
Dynamics of the immune reaction to pancreatic cancer from inception to invasion. |
17909062 |
Cancer Res |
Early diagnosis of pancreatic cancer: neutrophil gelatinase-associated lipocalin as a marker of pancreatic intraepithelial neoplasia. |
18392050 |
Br J Cancer |
Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy. |
17234748 |
Cancer Res |
Engineering antibodies for clinical applications. |
17512622 |
Trends Biotechnol |
ErbB2 growth factor receptor, a marker for neuroendocrine cells? |
15775699 |
Pancreatology |
Evaluation of MUC6 mucin tandem repeats. |
15716126 |
Biochim Biophys Acta |
Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis. |
23754791 |
Int J Cancer |
Functions of tumorigenic and migrating cancer progenitor cells in cancer progression and metastasis and their therapeutic implications. |
17273942 |
Cancer Metastasis Rev |
Generation and characterization of anti-MUC4 monoclonal antibodies reactive with normal and cancer cells in humans. |
14729877 |
J Histochem Cytochem |
Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer. |
18515410 |
Gut |
Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells. |
17595659 |
Br J Cancer |
Human RNA polymerase II-associated factor complex: dysregulation in cancer. |
17599057 |
Oncogene |
Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis. |
14744777 |
Cancer Res |
Interactions between MUC1 and p120 catenin regulate dynamic features of cell adhesion, motility, and metastasis. |
24371222 |
Cancer Res |
Interplay of distinct growth factors during epithelial mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies. |
17355951 |
Ann Oncol |
K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling. |
17332339 |
Cancer Res |
Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas. |
17349581 |
Cancer Cell |
Loss of fibulin-2 expression is associated with breast cancer progression. |
17456760 |
Am J Pathol |
MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer. |
24204560 |
PLoS One |
Modelling oncogenic Ras/Raf signalling in the mouse. |
19201597 |
Curr Opin Genet Dev |
MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion. |
17974963 |
Cancer Res |
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer. |
22869720 |
Proc Natl Acad Sci U S A |
MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster. |
24143167 |
PLoS One |
MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer. |
18475301 |
Br J Cancer |
MUC4 expression correlates with poor prognosis in small-sized lung adenocarcinoma. |
17126950 |
Lung Cancer |
MUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas. |
16049287 |
J Clin Pathol |
MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms. |
16799633 |
Oncogene |
MUC4 is a novel prognostic factor of extrahepatic bile duct carcinoma. |
16857800 |
Clin Cancer Res |
MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells. |
18381409 |
Cancer Res |
MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins. |
17406026 |
Mol Cancer Res |
MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells. |
19010895 |
Cancer Res |
MUC4-expressing pancreatic adenocarcinomas show elevated levels of both T1 and T2 cytokines: potential pathobiologic implications. |
17032197 |
Am J Gastroenterol |
MUC4-mediated regulation of acute phase protein lipocalin 2 through HER2/AKT/NF-κB signaling in pancreatic cancer. |
24240113 |
Clin Cancer Res |
Mucin expression in pleomorphic adenoma of salivary gland: a potential role for MUC1 as a marker to predict recurrence. |
15280401 |
J Clin Pathol |
Mucins in cancer: protection and control of the cell surface. |
14681689 |
Nat Rev Cancer |
Notch 2-positive progenitors with the intrinsic ability to give rise to pancreatic ductal cells. |
15924149 |
Lab Invest |
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. |
21734707 |
Nature |
Optimization of radioimmunotherapy of solid tumors: biological impediments and their modulation. |
17309914 |
Clin Cancer Res |
Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis. |
22977192 |
Clin Cancer Res |
Overexpression of GalNAc-transferase GalNAc-T3 promotes pancreatic cancer cell growth. |
21625220 |
Oncogene |
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells. |
17404500 |
Cancer Biol Ther |
Pancreatic enzyme extract improves survival in murine pancreatic cancer. |
15097858 |
Pancreas |
Pathobiological implications of MUC16 expression in pancreatic cancer. |
22066010 |
PLoS One |
Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations. |
16397221 |
Cancer Res |
Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression. |
18625714 |
J Biol Chem |
Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells. |
17545600 |
Cancer Res |
Ras-driven transformation of human nestin-positive pancreatic epithelial cells. |
18374182 |
Methods Enzymol |
Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers. |
17979879 |
J Cell Mol Med |
Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies. |
16195239 |
Carcinogenesis |
Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies. |
16258363 |
Pancreas |
Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies. |
17786164 |
Clin Pharmacol Ther |
Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer. |
18791122 |
Gut |
Recent progress on tissue-resident adult stem cell biology and their therapeutic implications. |
18288619 |
Stem Cell Rev |
Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases. |
16487661 |
Biochim Biophys Acta |
Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells. |
18322957 |
World J Gastroenterol |
Rosiglitazone and Gemcitabine in combination reduces immune suppression and modulates T cell populations in pancreatic cancer. |
22864396 |
Cancer Immunol Immunother |
Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer. |
19633682 |
Oncogene |
Sonic hedgehog promotes desmoplasia in pancreatic cancer. |
18829478 |
Clin Cancer Res |
Stem cells: a revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. |
17671448 |
Clin Pharmacol Ther |
Structure, evolution, and biology of the MUC4 mucin. |
18024835 |
FASEB J |
Targeting of cancer stem/progenitor cells plus stem cell-based therapies: the ultimate hope for treating and curing aggressive and recurrent cancers. |
18427384 |
Panminerva Med |
The human homologue of the RNA polymerase II-associated factor 1 (hPaf1), localized on the 19q13 amplicon, is associated with tumorigenesis. |
16491129 |
Oncogene |
The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation. |
17215257 |
Glycobiology |
The MUC gene family: their role in the diagnosis and prognosis of gastric cancer. |
18830939 |
Histol Histopathol |
The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. |
20697347 |
Oncogene |
Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway. |
14583090 |
Biochem J |
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. |
15894267 |
Cancer Cell |
Tumor suppression by collagen XV is independent of the restin domain. |
22531369 |
Matrix Biol |