Breast Reference Set Application: Anu Mathew-Meso Scale (2012)
- Abbreviated Name
- Breast Ref Set App: Mathew (2012)
- Lead Investigator
- Mathew, Anu — Meso Scale Diagnostics
- Coordinating Investigator
- Zheng, Yingye — Fred Hutchinson Cancer Center
- Involved Investigators
Abstract
No abstract availalbe.
Aims
Using a subset of plasma samples (n=505) from the reference set, we analyzed 90 proteins by multiplexed immunoassays for their potential utility as diagnostic markers.
Analytic Method
Two vials of each sample (400 μl total volume) were provided to Meso Scale Diagnostics, LLC. (MSD®) for testing using a selection of MSD’s multiplexed assay panels. The samples were thawed and further aliquoted to strip-tubes before freezing on dry ice and storage at -80°C. This approach minimized the number of freeze-thaw cycles to no more than two for each sample.
Outcome
Using a subset of plasma samples (n=505) from the reference set, we analyzed 90 proteins by multiplexed immunoassays for their potential utility as diagnostic markers.
Publications
Biomarkers
- ADIPOQ
- AFP
- AKR1B1
- AKR1C2
- ALPL
- ANXA1
- BCL2L2
- BGLAP
- CA125
- CA15-3
- CA19-9
- CCL11
- CCL13
- CCL17
- CCL2
- CCL22
- CCL26
- CCL4
- CCL5
- CDH1
- CDH3
- CEACAM5
- CHGA
- CRP
- CRYAB
- CSF1
- CXCL10
- CXCL8
- EGFR
- ERBB2
- FABP5
- FGF2
- FLT1
- FLT3LG
- GCLM
- GLO1
- GPI
- GSTM1
- GSTM2
- HGF
- ICAM1
- IFNG
- IL10
- IL12
- IL13
- IL18
- IL1B
- IL2
- IL4
- IL5
- KDR
- LBP
- MAGEA4
- MAPK14
- MBD1
- MET
- MMP1
- MMP10
- MMP2
- MMP3
- MMP9
- MSLN
- NECTIN4
- NME2
- ODC1
- Osteopontin
- PIGF
- PRDX4
- PRL
- PSA
- PSAT1
- PTPA
- RAC1
- S100A4
- S100A6
- SAA@
- SAT1
- SATL1
- SERPINB3
- SFN
- SOST
- TEK
- TIMP1
- TNF
- TNFRSF11B
- TNFRSF1A
- TNFRSF1B
- VCAM1
- VEGFC
- VEGFD
Data Collections
- No data collections available at this time for this protocol.
Team Project
- Start Date
- May 30 2012
- Estimated Finish Date
- May 29 2013
- Finish Date
- Dec 3 2014
- Protocol ID
- 350
- Protocol Type
- Reference Set
- Fields of Research
-
- Proteomics
- Collaborative Group
- Breast and Gynecologic Cancers Research Group
- Cancer Types
-
- Malignant neoplasm of breast